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With this, the energy expenditure (EE), standardized for BW, was calculated using the following formula: EE=(3.185 + 1.232 x RER) x V02

The different doses used could be partly responsible for the differences between the responses to peripheral and central injections, but it is notable that the direction of the difference was not the same after LV or 4V injection, making it unlikely that it was simply a dose-related artifact

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Typical symptoms of PFE include dyspnea, hypotension, tachycardia, hypoxemia, and altered mental status