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6.3 Neural and hormonal pathways involved in gut-brain communication The communication between the gut and brain involves complex neuronal and hormonal networks that might be disturbed following I/R injury

However, as the malignancy progresses, due to difficulties in vascular and immune cell infiltration, more glucose may be converted to lactate through anaerobic glycolysis, leading to its accumulation and potentially promoting tumor progression further

Potential Reactions: Some patients may experience mild or temporary effects such as injection site irritation, fatigue, nausea, headaches, or other unexpected symptoms

So all these doctors that say, ohh, obesity is a complicated, No, it's not