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[DOI] [PubMed] [Google Scholar] 41.Hirshberg B, Livi A, Bartlett DL, et al
Oxidative stress which leads to the excessive production of ROS (a set of free radicals and non-free radical oxygen) can impair the integrity of vascular walls (16)
29.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others References Ehlers, E
However, there seems to be a contradictory result between adipocytes and ferroptosis, as shown by the proliferation of adipocytes despite being under ferroptosis conditions ( 2 O 2 and found that an increase in ROS enhanced adipocyte apoptosis ( In conclusion, on the basis of these studies, this review speculated that there may be two mechanisms of ferroptosis leading to obesity: (i) In the autonomic nervous system, vagus and parasympathetic nerves in some organs or tissues may be affected by ferroptosis and become dysfunctional, while the inflammatory factors released from adipocytes lead to excessive sympathetic activation and hypothalamic neuronal ferroptosis which promotes the development of obesity through a series of processes
