glp 1 agonist drug GLP-1 Agonists: A Comprehensive Overview GLP-1 and Dual GIP/GLP-1 Agonists

Shi et al., 2001)

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells

Baynes JW

[6] Preclinical studies in animal models suggest that GLP-1 receptor activation may: Promote neuroplasticity and neurogenesis (formation of new neurons) in the hippocampus, a region often showing reduced volume in depression Modulate neurotransmitter systems , particularly dopamine and serotonin pathways involved in mood regulation and reward processing Reduce neuroinflammation , which is increasingly recognised as contributing to depressive disorders Enhance brain-derived neurotrophic factor (BDNF) expression, a protein crucial for neuronal health and resilience Metabolic improvements associated with GLP-1 therapy may also contribute indirectly to mood benefits