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In addition to these ingredients, e-cigarettes may contain heavy metals (nickel, tin, lead), diacetyl (linked to lung disease), benzene (found in car exhaust), and cadmium (a toxic metal that can cause respiratory problems)

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In line with the hypothesis that epithelium from control smokers is better protected against cigarette smoke-induced changes in mitochondrial function, OXPHOS complex levels were not (persistently) higher in PBECs from smokers with normal lung function than from never-smokers, although OXPHOS complex II, III and VF1 were increased upon long-term CSE exposure in BEAS-2B

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