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By inhibiting NNMT, 5-Amino-1MQ may spare nicotinamide for NAD+ synthesis, thereby activating SIRT1 (Sirtuin 1) pathways associated with mitochondrial biogenesis and fat oxidation
PubMed Percevault S, Charpiat B, Leboss F, Mabrut JY, Vial T, Colom M
Active constituents such as harpagoside provide neuroprotection, suggesting indirect benefits in neuroendocrine disturbances associated with thyroid dysfunction (146, 147)
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