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on 24 patients with generalized vitiligo and 20 healthy controls found statistically significant higher levels of superoxide dismutase activity in erythrocytes, serum MDA, and nitric oxide (NO) and statistically significant lower levels of glutathione and glutathione peroxidase in the patients of vitiligo compared to the controls.[] Secondary to the oxidative stress, the polyunsaturated fatty acids undergo peroxidation resulting in formation of free radicals

Moreover, this glucose control intervention increased the risk of hypoglycemic episodes (73)

After FOXO4-DRI treatment, the staining of FOXO4 and p53-pS15 became weaker in the nucleus at 48 h and then disappeared with an accumulation in the cytoplasm at 72 h, especially in keloid fibroblasts

Ili IR, Stojanovi NM, Radulovi NS, ivkovi VV, Randjelovi PJ, Petrovi AS, Boi M, Ili RS (2019) The quantitative ER immunohistochemical analysis in breast cancer: detecting the 3 + 0, 4 + 0, and 5 + 0 Allred score cases