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Patel concurs and adds that every once in a while people who use his low-dosage (100 or 175 milligrams) topical treatment will experience a minor rash that quickly dissipates. These individuals should lower the dose to better suit their needs, he advises

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Augies Quest to Cure ALS provides this information based on public information and recommends you speak to your neurologist to determine if this is a helpful option for you

For Indian skin (Fitzpatrick IVVI) Retinol may carry heightened irritation risk in Fitzpatrick IV-VI skin types and requires cautious introduction due to increased melanin content and barrier sensitivity