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Stress and anxiety create a complex interplay of physical and emotional factors

In: Leenher AP, Lambert WE, Bocxlaer JF, editors

This can be stated given the particular counteracting effect on convulsions (i.e., insulin hypoglycemic convulsions [62], and paracetamol over-dose-convulsions, progressive hepatic encephalopathy with generalized convulsions [61]), the improved conscious/unconscious/death ratio in trauma brain injury mice [78], attenuated/counteracted cerebellar ataxia, fore and hind limbs disabilities in cuprizone rats [80], and counteracted sedation/unconsciousness (diclofenac [108], ibuprofen [107])

While it might be easier said than done, the best thing you can do to prevent pain is to simply relax your arm or shoulder before the injection