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In this pathway, the transcription of p53 activates the expression of pro-apoptotic proteins Bax/Bak and inhibits the expression of anti-apoptotic proteins Bcl-2/Bcl-xL, resulting in increased mitochondrial membrane permeability and cytochrome c release, which in turn activates the caspase-9/3 cascade reaction and ultimately causes apoptosis (Aranda-Rivera et al., 2021
Chemically composed of three amino acids cysteine, glutamic acid, and glycine it helps neutralize harmful free radicals, supports liver function, and maintains the integrity of cells and tissues
D., Earle, D
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