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doi: 10.1007/s11914-015-0292-x

It is presumed that the peroxisomes, especially abundant in Muller cells and RPE, due to the enzymes they contain: catalase and aldehyde dehydrogenase, may be involved in the local metabolism of methanol, which determines the formation of formaldehyde and formic acid (Garner et al

Transfection with hsa-let-7c low-expression virus brought about the upregulation of IGF-1R and the enhanced odonto/osteogenic differentiation in IGF-1-treated SCAPs, as indicated by the upregulation of several odonto/osteogenic markers ( DMP1 /DMP1, COL-I /COL-I, ALP, RUNX2 /RUNX2, OSX /OSX, DSPP /DSP and OCN /OCN) in vitro

Mildly affected patients experience a compensated haemolytic anaemia because mutations affect stability of the enzyme