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Consistently, direct infusion of exendin-4 into the NAc mitigated alcohol self-administration in rats with similar results in alcohol consumption with systemic administration [45], indicating that the modulation of dopamine reward system is principally involved in overeating and obesity

Expected outcome: Potentially improved digestive comfort

Oprah has also been clear about how she uses her weight-loss medication

This approach suits individuals new to GLP-1 therapy, those with complex medical histories, or patients who value frequent dose adjustment guidance without coordinating separate pharmacy and clinical relationships