is glp 2 tirzepatide GLP2- super helpful for my RA, Addisons and Crohns. I don’t lose weight on it, I protect my gut lining, improve nutrient uptake and lower pro inflammatory cytokines. Thank you GLP-2 (Tirz) 10mg - NextEdge

Mller, T

Common side effects (5% or more of patients) Nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite, indigestion, injection site reactions Serious side effects (rare) Pancreatitis stop Zepbound and seek emergency care for severe, persistent abdominal pain radiating to the back Gallbladder disease upper right abdominal pain, fever, jaundice Severe allergic reactions facial swelling, throat tightening, difficulty breathing Acute kidney injury usually from dehydration due to prolonged vomiting or diarrhea Hypoglycemia most likely when combined with insulin or sulfonylureas in diabetic patients Increased resting heart rate Boxed warning: Tirzepatide caused thyroid C-cell tumors in animal studies

GLP-1 and Appetite Regulation

Quick Answer: Yes, Zepbound (tirzepatide) causes diarrhea in 18-26% of patients, making it one of the most common gastrointestinal side effects reported in clinical trials