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Studies show that the XPC variants are associated with increased DNA adduct levels after aflatoxin B1 exposure, increasing liver cancer risk.[ref][ref][ref] This means that for people who both accumulate more DNA damage from mycotoxins (because of detox variants) and repair it less efficiently (because of XPC variants), the longterm cancer risk from chronic exposure is significantly higher

Disclaimer Metformin's use for anti-aging or weight-loss support is not FDA-approved, and scientific consensus on these off-label benefits is still evolving

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Kisspeptin Kisspeptin binds to its receptor on GnRH neurons and drives GnRH release, positioning it as an upstream regulator of subsequent reproductive hormone cascades