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One of the distinctive features of IGF-1 LR3 is its reduced affinity for insulin-like growth factor binding proteins (IGFBPs), a family of proteins that regulate the distribution and accessibility of IGFs within circulation

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In the TRIUMPH-1 Phase 3 trial, participants on the maximum dose of retatrutide (12 mg) lost an average of 28.3% of their body weight after 80 weeks, and up to 30.3% after 104 weeks in the study extension

Its the lack of an holistic approach which is failing our patients