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While office BP monitoring is most practical with improved accuracy achieved after 510 minutes rest, repeated automated measures, ideally on both arms7,8 sustained elevated readings using a 24-hour ambulatory BP monitoring (24-h ABPM) independently predict increased cardiovascular risk of 27% for every 10 mmHg increase in 24-h ABPM SBP.9 Elevated nighttime BP, in particular, has been associated with increased risk of cardiovascular events including stroke and myocardial infarction.9 Twenty percent of individuals demonstrate white-coat hypertension, defined as elevated office BP but normotensive 24-h ABPM.10 White-coat hypertension, however, has been associated with functional and structural cardiovascular abnormalities, including reduced arterial elasticity, left ventricular diastolic dysfunction, and enlarged arteries, similar to persistent hypertension.11 Therefore, treatment of individuals with white-coat hypertension may still be of benefit

10.1289/ehp11813