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Ghrelin and Synthetic GH Secretagogues Protect Rat Hearts From Ischemic Damage. Basic research in cardiology.Study breakdown PubMed 10RPEP-08773Lu, Zengbing et al

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By increasing insulin sensitivity and glucose uptake in the body, semaglutide helps to maintain healthy blood sugar levels, even in individuals with insulin resistance

In the SUSTAIN 6 CV outcomes trial (CVOT), once-weekly semaglutide (0.5 or 1.0 mg) added to standard of care significantly reduced the occurrence of a first major adverse CV event (MACE: CV death, nonfatal myocardial infarction [MI], or nonfatal stroke) vs placebo over 2 years in 3297 subjects with T2D and high CV risk [12]