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This blog is part of an ongoing series on A Brave New World: Therapeutic Area Deep Dives

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However, we were not able to detect this change in HT1080 cells with either 40 M cholesterol or desmosterol treatment up to 6 h, which is much longer than needed for these two sterols to take effect (3 h pretreatment plus 2 h RLS3 treatment in lipid peroxidation assay, Fig