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Using this approach, a set of SNP across the whole genome is examined to identify the most relevant variants associated with the disease (Spritz, 2012)
The increased endothelial cell permeability is generated by TGF1 via SMAD3-dependent signaling, which upregulates matrix metalloproteinase-9 and downregulates claudin-5
Additionally, like all health-related content on this website, this review was thoroughly vetted by one or more members of our Medical Review Board for accuracy
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