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At present, there are a few experimental studies that have used medical laboratory animals placed in a hypoxic environment to simulate acute altitude sickness [6, 8]

2012 Jan;9(1):79

This might be due to the fact that GLP-1RAs have a delaying effect on gastrointestinal emptying, which could exacerbate gastrointestinal disorders or predispose to the development of prior gastrointestinal disorders