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It is safe to double in times of increased stress

The SURPASS-CVOT trial, where dulaglutide at the dose of 1.5 mg/week or at the highest tolerated dose, is the comparator, has a distinctive design from the other trials: the primary endpoint is the time to the first manifestation of any major adverse CV event (MACE), defined as myocardial infarction, stroke or CV death

2.3 Hemoglobin oxidation studies Prepare stocks of iron, glutathione, deferoxamine, and deferiprone solution and dilute them with distilled water to reach the exact quantities and concentrations required for the experiment

Patients switching from liraglutide to semaglutide should stop liraglutide on the day of the first semaglutide 0.25 mg dose