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In CYB5R3-deficient conditions, MetHb builds up, glutathione (GSH) levels rise in response to oxidative stress, and RBCs display morphological changes such as microcytosis, acanthocytosis, and increased membrane fragility ( Due to the lack of mitochondria, RBCs depend on the pentose phosphate pathway (PPP) to produce reducing equivalents in the form of NADPH

Choline Choline is responsible for transporting fat to be metabolized into energy

It may also help with benign prostatic hyperplasia (BPH) by reducing prostate enlargement and improving urinary symptoms

194 GLP-1 also acts directly on the liver, inhibiting glycogenolysis, promoting glycogen synthesis, and regulating the expression of lipid metabolism-associated genes, thereby reducing hepatic fat accumulation and improving glucose and lipid homeostasis along the gutliver axis