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In sepsis models, propofol is currently employed to assist mechanical ventilation in patients with sepsis combined with respiratory failure, but it also may be a potential independent risk factor for severe polyneuropathy or a synergistic effect [173]
Pharmacological activation of pyruvate kinase M2 inhibits CD4 + T cell pathogenicity and suppresses autoimmunity
In an unrelated mouse model of tumor metastasis, ILC2-dependent eosinophilia impaired the IFN production and cytotoxic activity of NK cells, presumably via modulation of the glucose metabolism (Schuijs et al, 2020)
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