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395 The remaining liver undergoes metabolic reprogramming after injury, adjusting the balance between gluconeogenesis, glycogen synthesis, and glycolysis to meet the substantial energy, substrate, and signaling demands required for repair and regeneration (Fig

The brains restricted antioxidant capacity, high energy demand, high levels of transition metals, such as iron and copper, and a high concentration of polyunsaturated fatty acids which can be subjected to lipid peroxidation [103,104,105] make the nervous system particularly vulnerable to oxidative stress [106]

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Symptoms of each psychiatric disorder are described in Figure 1