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The immunomodulators azathioprine and 6-mercaptopurine are purine analogues metabolized via a well described enzymatic pathway, with the 6-thioguanine nucleotides (TGN) determined to be the active metabolite

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David Greybeard had the most beautiful eyes of them all, large and lustrous, set wide apart, she writes in her book Through a Window. They somehow expressed his whole personality, his serene self-assurance, his inherent dignity and, from time to time, his utter determination to get his way. But chimps can also be shockingly violent