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Furthermore, the bronchial epithelia of these animals showed mild hyperplasia, lymphoid follicles in the bronchial epithelial layer increased, focal alveolar inflammatory changes occurred, a large amount of lymphocyte infiltration occurred in the bronchial wall, and local squamous metaplasia occurred

6 hours: 12.5% remains

This chemical interaction not only leads to physical dependence but also results in changes in brain function, making individuals anxious or irritable when they try to quit