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Yauk CL, Berndt ML, Williams A et al (2007) Mainstream tobacco smoke causes paternal germ-line DNA mutation

Frequent marijuana users have been shown to have: An 88% higher risk of developing coronary artery disease An 81% increased risk of stroke Among those who had been diagnosed with premature cardiovascular disease - men younger than 45 and women younger than 55 - frequent marijuana users had: 2.3 higher chances of coronary artery disease or myocardial infraction 1.9 times higher risk of stroke Another study found that marijuana use leads to an increased risk of cardiovascular complications and found that cannabis use is a possible risk factor for cardiovascular disease in young adults