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People with the following conditions should speak with a healthcare professional before using nicotine products: High blood pressure (hypertension) Heart disease Previous heart attack Stroke history Irregular heartbeat Pregnancy Nicotine may complicate cardiovascular management, particularly when blood pressure is already difficult to control

This work was supported by the National Institute of Dental and Craniofacial Research and National Institute on Drug Abuse of the National Institutes of Health [R01DE031863, R21DA058342] and the University of California Tobacco-Related Disease Research Program [T31IR1839, T32IR5144, T33IR6680] .

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To permanently remove smoke smells, the interior must be cleaned and the odor source neutralized