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These risks include: Various types of cancer (lung, mouth, throat, esophagus, etc.) Cardiovascular diseases (heart disease, stroke) Respiratory issues (chronic obstructive pulmonary disease, emphysema) Increased risk of infections Reduced fertility and pregnancy complications Premature aging and skin problems Nicotine: Addictive but Less Harmful in Isolation While nicotine is highly addictive, its health impacts when isolated from tobacco are generally considered less harmful alternatives to smoking: Not directly linked to cancer May have some cardiovascular effects (increased heart rate, temporary rise in blood pressure) Potential impact on brain development in adolescents and young adults Possible effects on wound healing and insulin sensitivity Its important to note that while less harmful than tobacco, nicotine is not risk-free

[105] [106] [107] Gorlin's sign in a case of EDS Keratoglobus in a case of EDS with brittle cornea syndrome Because it is often undiagnosed or misdiagnosed in childhood, some instances of EDS have been mischaracterized as child abuse

Selective selection of studies Professor Peter Shields, Emeritus Professor of Medical Oncology at Ohio State University, notes that Bernard Stewart's report does not really add anything new

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