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Environmental tobacco smoke such as second-hand smoke is a potent cocktail of over 4000 different substances and chemicals - some in particulate form (over a wide range of particle sizes from over 10 microns to as small as 0.01 microns) and some in the form of gas molecules (which are even smaller)

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carbon monoxide, free radicals, etc , impede the blood from being transported across the body

Smoking more harmful than HIV in patients adhering to ART For patients with HIV who adhere to their treatment regimen but smoke cigarettes, smoking reduces life expectancy by about twice as much as HIV, according to the results of a United States-based modelling study