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Future studies are needed to better understand the clinical significance for the magnitude of the effect by PG and VG, varying ratios of the two and longer duration of use as well as effects of flavors. Journal reference: Effects of Electronic Cigarette Constituents on the Human Lung: A Pilot Clinical Trial Min-Ae Song, Sarah A

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Facing declining collections from property and income taxes in the wake of the Great Depression, 19 states jumped on board in the 1930s, and by 1950 40 states and the District of Columbia were levying a tax on cigarette sales