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Similar findings were made by Martin et al

Oxidative stress leads to sperm dysfunction ( Genetic factors Genetic factors play an important role in the most serious spermatogenic disorders, such as severe oligozoospermia or azoospermia ( In infertile men, the incidence of chromosomal abnormalities has been reported to range from 5 to 15%, indicating that these abnormalities lead to non-obstructive azoospermia (NOA) ( AZF a (792 kb), AZF b (6.2 Mb), and AZF c (4.5 Mb) which contain several genes responsible for male fertility ( AZF c region containing eight gene families causes progressive deterioration of spermatogenesis and, consequently, azoospermia eventually leads to phenotypic changes in infertile men ( Spermatogenesis is thought to be regulated by as many as 2,000 genes, of which 600900 genes seem to be expressed only in the male reproductive line

Glutathione contributes by protecting neural tissue from oxidative damage

10.1111/j.1464-410X.2012.11185.x BJU Int