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Hypertensive heart disease, some kinds of respiratory diseases and ischemic disorders of the intestines were also more likely to kill smokers than nonsmokers, the study authors calculated

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The interaction between the cigarette smoke and the epithelial lining fluid (ELF) enables further production of ROS in the airways, since both cigarette smoke and ELF contain metal ions, such as iron, which catalyze the production of free radicals [93]

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