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[I]t is appropriate to consider potential hazards of e-cigarettes, the authors wrote, but they emphasized that this analysis should be carried out relative to the impacts of smoking: [A]s smoking cessation is associated with a reduction in respiratory symptoms in people with respiratory disease, many smokers who switch to an e-cigarette are likely to experience improvements in respiratory symptoms

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The brand originated in Durham, North Carolina, USA, gaining widespread fame through advertising campaigns in the 1940s and 1950s featuring Bing Crosby, Perry Como, Bob Hope, Paul Douglas, and Ronald Reagan on NBC radio programs

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