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10.1016/j.fct.2017.07.018 134 OzaM

5(2):e1000313

In Shi et al, Lactobacillus rhamnosus GG (LGG) was shown to modulate T-bet expression and Th1 differentiation via two metabolite-mediated pathways regulation of T-bet, EPS engage the TLR2/MyD88 dendritic cell pathway with subsequent production of IL-12 and resultant STAT4 phosphorylation that directly amplifies T-bet, and SCFAs, such as butyrate, repress histone deacetylases (HDACs), enhancing Tbx21 promoter acetylation to increase T-bet expression

There was no obvious trend for change neither in the size nor in the PDI values of diluted nanocarriers stored at 4 C for 6 months (Table S1b)