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Brandt tells the story of its quick rise from a minuscule portion of the tobacco trade (during the reign of the spittoon) to the ubiquitous product of today

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beginners , a neutral blend is usually recommended, as it allows for a smoother transition and does not overwhelm the palate

Funding This study was supported by the General Project of Key Research and Development Plan of Shaanxi (Grant Number: 2023YBSF424), the General Project of Basic Research Plan of Shaanxi (Grant Number: 2024JC-YBMS-700), and the Phoenix Introduction Plan Project of Tangdu Hospital, Air Force Military Medical University (Grant Number: 2022YFJH007)