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Although oxidative stress is known to induce post-translational modifications/damage to mitochondrial proteins [25, 26], it is currently unknown whether mitochondrial structure and function in airway epithelial cells are affected by cigarette smoke [27, 28], and whether these changes are present in COPD epithelium

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By initiating conversations and building trust with their young patients, doctors can create an open and supportive environment for discussions about tobacco use