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Much of the harm from drug use is not inherently related to consumption, but is heavily influenced by the environmental conditions of the drug use 2 and this additional hazard is not included in a drug ranking based on (animal) toxicology

20 Prior to starting treatment for hypertriglyceridemia, reversible causes of hypertriglyceridemia, including medication effect (eg, exogenous estrogen or some diuretics) or some medical conditions (eg, hypothyroidism or excessive alcohol use) should be corrected if possible

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