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According to Donihi and Sethi, short-term side effects may include: Increased appetite Fluid retention or edema Upset stomach Acne Difficulty sleeping Tremors Sweating Rapid heartbeat Change in mood (either hyper or sad) Those taking prolonged courses of prednisone (longer than three weeks) may experience more serious side effects, such as: Eye problems, such as glaucoma or cataracts Mood changes, which can cause people to be more irritable, anxious or depressed Thinning of the skin, which can cause the skin to bruise more easily Elevated blood pressure Elevated glucose levels Weight gain (due to fluid retention and/or increased appetite) Redistribution of body fat to the face, abdomen or back of the neck (sometimes called a buffalo hump) Slower healing of cuts and bruises, which increases the risk of infection Osteoporosis, bone fractures, bone thinning and loss of bone Lowered immunity, which results in increased risk of infection To read more about how prednisone has affected people with chronic illness in our Mighty community, check out the stories below : 9 Side Effects of Prednisone Ive Experienced How Prednisone Has Affected My Teeth Prednisone: The Marvelous Monster in My Life 6 Wacky Side Effects of Prednisone They Dont Tell You About Dear Prednisone, I Would Not Be Where I Am Today Without You How Can You Manage the Side Effects of Prednisone

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