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Closer examination of the skin with a magnifying glass reveals lines under the skin, which are produced by the mites burrowing

They have a greater chance of developing the blood cancer known as Lymphoma, as well as respiratory conditions such as bronchitis and asthma

Science 341 , 903906 (2013)

This is, sadly, where things are going wrong - people are using chemicals like diacetyl in their liquids, in some cases as a base for mixing in other chemicals like THC (tetrahydrocannibinol - the psychoactive ingredient in cannabis) and this is causing the health issues that has skewed public perception of vaping, everywhere