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Gutkha has been strongly implicated in an increase in oral submucous fibrosis, a very malignant and debilitating condition with no cure
Because most RYO users roll less than 0.8 grams of tobacco per cigarette, using as little as 0.5 grams per cigarette, 58 RYO tobacco provided a cheaper alternative to factory-made cigarettes (attracting less excise per cigarette)
Dopamine is the feel-good neurotransmitter
Hormones categories were included as the dependent variables in a multiple regression analysis to test the relationship with WP smoking level (independent variable) after adjustment for age and cigarette smoking
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