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Tobacco companies knew early on that lifelong smokers typically begin smoking before the age of 18, and while they couldnt ever officially market to what the industry called replacement smokers, they have crossed about every line there is to cross (see: Joe Camel)

Reynolds is introducing special-edition packs of Camel cigarettes that play off the images of cities that have a hip image drawing fire from antismoking groups who say they are marketing to youth

The same review compiled epidemiological studies in humans demonstrating that early life exposure to arsenic is associated with deficits in intelligence and memory

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