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At smaller physiological levels, ROS can also regulate essential signaling pathways such as mitogen-activated protein kinases (MAPK), phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, Akt), apoptosis signal-regulating kinase 1 (ASK1), and NAD + -dependent deacetylase Sirtuin 1 (SIRT1)-Forkhead box class O (FoxO)/TRP53 transcriptions [196, 198, 199]
1921 : The G.H
Equality and freedom ka yeh matlab nahi hai ki aap apne lungs kharab kar lein.' Actress Sonali Kulkarni, who has not smoked on screen but has done it for one of her plays, says, 'Yes, women are smoking more and I plead with my colleagues and friends to quit and lead a healthy life
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