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Description

Glutamine metabolism inhibition, using agents such as CB-839, has shown potential to suppress TCA cycle-mediated energy production and disrupt redox homeostasis, particularly in CRC subtypes resistant to 5-FU and oxaliplatin [145]

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Petersen J, Ludwig MQ, Juozaityte V, Ranea-Robles P, Svendsen C, Hwang E, et al

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