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These signaling pathways lead to the production of different sets of pro-inflammatory cytokines, respectively, via NF-B transcription factor pathway activation, and via MAP kinases phosphorylation and subsequent activation of type I PI3-kinase/Akt and transcription factors AP-1 and CREB [24]

Md Yusof MY, Arnold J, Saleem B, Vandevelde C, Dass S, Savic S, et al

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Benoist 2014, PMID 25187433, retracted 2025 per notice PMID 40312093) is potentiation of hepatocyte growth factor (HGF) signaling at the c-Met (MET) receptor, driving dendritic spine formation and synaptogenesis via PI3K-AKT