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"Our analyses show that there is significant toxicity in harm reduction products, and reduction of carcinogens in harm reduction mainstream smoke does not necessarily reduce the toxicity of unfiltered sidestream smoke." Researchers developed tests with human embryonic stem cells, which are similar to young embryos, to compare the toxicity of mainstream (inhaled) smoke and sidestream smoke from both conventional and harm reduction cigarette brands

The camera is positioned directly above the ashtray, offering a birds eye perspective of the refuse left after smoking

In addition, RNA sequencing analysis revealed that thirdhand smoke exposure caused endoplasmic reticulum stress and activated p53 (tumor suppressor) signaling

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