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Pump settings and bolus strategies may need review because appetite and meal patterns can change

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This is pretty much exactly what we expect from the trials, but it's always nice to have replications and some assurance about the potential viability of using observational data, since it matches at least some of the causal data.There's also similarity to trial side effect profiles: In trials, tirzepatide has fewer and milder side effects while delivering more weight loss

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