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Diacetyl is the chemical previously used in microwave popcorn to add a strong buttery flavor but found to cause irreversible lung damage and leading to the term popcorn lung disease. If vaped in high concentration, these chemicals can cause respiratory stress, lead to cellular damage and an increased risk of respiratory infections and chronic lung diseases

The use of flavors in cigarettes, with the glaring exception of menthol cigarettes, was prohibited in 2009, but flavored cigars, e-cigarettes and other tobacco products are still made and sold with candy and fruit flavorings

[118] In May 2016, the European Union banned flavored cigarettes including menthols

Adolescents sometimes claim they "just got intrigued" or even thought smoking was "great"