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6 This finding is supported by a meta-analysis of studies from 1961 to 2003, which concluded that people with a history of smoking had a 6.8-fold higher risk of pharyngeal cancer compared to non-smokers

Among 4000 compounds of cigarettes, three matters have the most harmful effects on male fertility including nicotine (NIC), heavy metals, and benzopirin, where nicotine is known as the most dangerous matter and deadly toxin in tobacco that is detectable in both the serum and semen of smokers whose level is directly related to the cigarette use dose [15]

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