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states, incentivizing smuggling and illicit activity.[11] After New York, the highest rate of smuggling occurs in California (44.8 percent of consumption smuggled), New Mexico (45.5 percent), Washington (41.5 percent), and Minnesota (34.8 percent)

Through the end of 2021, sales were down more than 25 percent compared to sales from 2019

A large Cochrane review analyzing more than 60,000 participants across dozens of clinical trials concluded that combination nicotine replacement therapy improves long-term quit success by roughly 25 to 30 percent compared with a single product

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